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Research

The Department is involved in research and is publishing more regularly as listed. We have presented every year at the national ENT congress with distinction and have regularly come home with prizes as a result. The department hosted the 1st National ENT Head and Neck Congress which was held in Durban in November 2019.


 Publications

  1. Warren Kuhn. Review article: Acute mastoiditis and its complications, South African ENT review 2010; 2(2)34-40
  2. A M Campbell, W P Kuhn, P Barker. Vacuum-assisted closure of the open abdomen in a resource-limited setting. SA Journal of Surgery (2010); 48(4)
  3. Dr TK Naidoo, Dr SK Naidoo, Dr PK Ramdial. Oral cavity squamous cell carcinoma metastasis to the submandibular gland. Journal of Laryngology and Otology (2012) 126 (10) : 279-28
  4. Dr TK Naidu, Dr PK Ramdial, Dr SK Naidoo. Highly Active Antiretroviral Therapy-Associated Flare of Oropharyngeal Kaposi Sarcoma. Archives of Otolaryngology Head and Neck Surgery (2012) 138 (8): 1-3
  5. Ramdial PK, Sing Y, Ramburan A, Naidu TK, Samuel EY, Bagratee JS, Calonje E. Infantile donovanosis presenting as an external auditory canal polyps: A diagnostic trap. Am J Dermatopathol; (2012): 34(8): 818-821.
  6. Chotey NA, Naidu TK, Naidoo V, Naidoo J. Myopericytoma of the external auditory canal and tragus. J Laryngol Otol 2013: Aug 127(8): 805-8.
  7. Schlemmer KD; Naidoo SK. Complicated sinusitis in a developing country, a retrospective review. International Journal of Pediatric Otorhinolaryngology 77 (2013) 1174-1178
  8. Dr ZB Khuzwayo, Dr TK Naidu. Head and neck tuberculosis in KwaZulu-Natal, South Africa. Journal of Laryngology and Otology (2014) 128 (1) : 86-90
  9. BM Biccard, TE Madiba, on behalf of the SASOS investigators. The South African Surgical Outcomes Study: A 7-day prospective observational cohort study. SAMJ June (2015), vol 105 (6).
  10. Kløverpris HN, Kazer SW, Kuhn W, Ndung’u T, Leslie A. Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-1 Infection in the Absence of Viral Suppression. Immunity. (2016) Feb 16; 44(2):391-405.
  11. S Mahomed, M Archery, P Mutevedzi, Y Mahabeer, P Govender, G Ntshoe, W Kuhn, J Thomas, A Olowolagba, L Blumberg, KA Von Gottberg, P Moodley. An isolated outbreak of diphtheria in South Africa, 2015. Epidemiology and Infection. (2017) July 145(10): 2100-2108.
  12. du Plessis M, Wolter N,Kuhn W, Mlisana K, McCarthy K, von Gottberg A. Molecular Characterization of Corynebacterium diphtheriae Outbreak Isolates, South Africa, March-June 2015. Emerging Infectious Diseases. (2017) Aug 23(8): 1308-1315.
  13. Karrim N, Magula N, Saman Y. Antihistamines for motiob sickness (Protocol). Cochrane Database of Systematic Reviews 2017, Issue 7. Art. No : CD012715.DOI:10.1002/14651858.CD012715
  14. John Kutsukutsa1* , Tivani Phosa Mashamba-Thompson2 and Yougan Saman3. Tracheostomy decannulation methods and procedures in adults: a systematic scoping review protocol. . Systematic Reviews (2017) 6:239 DOI 10.1186/s13643-017-0634-0
  15. Roder J, Maehara T, Ngope A, Ramsuran D, Muenchhoff M, Adland E, Aicher T, Kazer SW, Jooste P, Karim F, Kuhn W, Shalek AK, Ndung’u T, Morris L, Moore PL, Pillai S, Kloverpris H, Goulder P, Leslie High-Frequency, Functional HIV-Specific T-Follicular Helper and Regulatory Cells Are Present Within Germinal Centres in Children but Not Adults. Frontiers in Immunology (2018) Sep 12(9): 1975
  16. Lufunda Lukama, Chester Kalinda, Colleen Aldous. Africa’s challenged ENT Services: Highlighting challenges in Zambia. BMC Health Services Research (2019); 19: 443-453
  17. Kutsukutsa, J., Rankhethoa, N., Pillay, J.S. et al. Streptococcus equi subsp. zooepidemicus and ‘Neighbourhood syndrome’ –extra-orbitocranial rhinosinusitis with reversible sudden loss of vision- a case report. BMC Ophthalmol 19, 117 (2019). https://doi.org/10.1186/s12886-019-1126-x
  18. Yakobi, A., Porterfield, J., Toman, et al, 2019. HIV, Tuberculosis, and Otogenic Intracranial Sepsis. Otology & Neurotology, 40(7), pp.e704-e712. doi: 10.1097/MAO.0000000000002290
  19. John Kutsukutsa, Desmond Kuupiel, Anna Monori-Kiss, Paula del Rey-Puechand Tivani Phosa Mashamba-Thompson. Tracheostomy decannulation methods and procedures for assessing readiness for decannulation in adults: a systematic scoping review. Int J Evid Based Healthc 2019: 17:000-000
  20. Bhamjee Aaqilah; le Roux Talita, Schlemmer Kurt, Perold Jenny; Cass Nicolize, Schroeder, Schlesinger Dani, Ceronio Deon, Vinck Bart. Parent-perceived challenges related to the pediatric cochlear implantation process and support services received in South Africa. International Journal of Pediatric Otorhinolaryngology 126 (2019) https://doi.org/10.1016/j.ijporl.2019.109635
  21. Brewis Bianca; Le Roux Talita, Schlemmer Kurt; Nauta Leone and Vinck Bart. Health-related quality of life in South African children who use cochlear implants. International Journal of Audiology. https://doi.org/10.1080/14992027.2019.1661531
  22. Z B Khuzwayo, B Enicker. Otogenic intracranial complications: a 10-year retrospective review in KwaZulu-Natal, South Africa. J Laryngol Otol (2020); 134: 3–7.
  23. Alveera Singh, Samuel W. Kazer, Julia Roider, Warren Kuhn, Philip Goulder, Alasdair Leslie, Henrik N. Kløverpris. ñ Innate Lymphoid Cell Activation and Sustained Depletion in Blood and Tissue of Children Infected with HIV from Birth Despite Antiretroviral Therapy. Cell Reports 32, 108153, (2020). https://doi.org/10.1016/j.celrep.2020.108153.
  24. Lufunda Lukama, Chester Kalinda, Warren Kuhn and Colleen Aldous. Availability of ENT Surgical Procedures and Medication in Low-Income Nation Hospitals: Cause for Concern in Zambia. Hindawi: BioMed Research International. Volume (2020), Article ID 1980123, 8 pages. https://doi.org/10.1155/2020/1980123
  25. Kurt Schlemmer, Liu Qingsong, Thomas Linder. Tympanoplasty with an Intact Stapes Superstructure in Chronic Otitis Media. J Int Adv Otol (2021); 17(4): 282-287
  26. J Naidoo, K Schlemmer. Intracapsular tonsillectomy versus extracapsular tonsillectomy. The Journal of Laryngology and Otology 2021; https://doi.org/10.1017/S0022215121002565
  27. Global Surgery 3 – Collaborator and Hospital Lead (Nivashen Pillay). Global variation is postoperative mortality and complications following cancer surgery : A multicentre prospective cohort study in 82 countries. : Lancet 2021, http://dx.doi.org/10.1016/S0140-6736(21) 00001-5
  28. The ASOS-2 Investigator (Nivashen Pillay). Effect of enhanced postoperative surveillance on mortality amongst adult surgical patients in Africa: A cluster randomised trial. : . Lancet Glob Health 2021; http://dx.doi.org/10.1016/S2214-109X(21)00291-6
  29. The ASOS-2 Investigators (Nivashen Pillay) Enhanced postoperative surveillance versus standard of care to reduce mortality among adult surgical patients in Africa (ASOS-2): a cluster-randomised controlled trial : Lancet Glob Health 2021; 9: e1391–401 Published Online August 18, 2021 https://doi.org/10.1016/S2214-109X(21)00291-6
  30. Rabiah Fardoos; Sarah K. Nyquist, Osaretin E. Asowata, Samuel W. Kazer, Alveera Singh, Abigail Ngoepe, Janifer Giandhari; Lindokuhle Sibiya; Warren Kuhn; Rishan Bipath. “HIV-specific CD8+ T-cells in tonsils express exhaustive TRM-like signatures.” bioRxiv (2021).
  31. Rabiah Fardoos; Osaretin Asowata; Sarah Nyquist; Yenzekile Zungu; Alveera Singh; Abigail Ngoepe; Ian Mbano; Farina Karim; Warren Kuhn; Fusi Madela; Vukani Manzini; Frank Anderson; Bonnie Berger; Tune Pers; Alex Shalek; Alasdair Leslie; Henrik Kløverpris. . “HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells “JCI Insight: 2021 Aug 23;6(16):1489
  32. Rabiah Fardoos; Sarah K. Nyquist; Osaretin E. Asowata; Samuel W. Kazer; Alveera Singh; Abigail Ngoepe; Janifer Gianghani; Søren Buus; Frank Anderson; Warren Kuhn; Farina Karim; Bonnie Berger; Tulio de Oliveira; James Z. Porterfield; ; Alex K Shalek; Alasdair Leslie; Henrik Kloverpris.
  33. Bhamjee, Aaqilah, Talita le Roux, De Wet Swanepoel, Marien Alet Graham, Kurt Schlemmer, and Faheema Mahomed-Asmail. “Perceptions of Telehealth Services for Hearing Loss in South Africa’s Public Healthcare System.” International journal of environmental research and public health 19(13) 2022: 7780 DOI:10.3390/ijerph19137780
  34. Bhamjee, Aaqilah, Talita le Roux, Kurt Schlemmer, Marien Graham, and Faheema Mahomed-Asmail. “Audiologists’ perceptions of hearing healthcare resources and services in South Africa’s public healthcare system.” Health Serv Insight (2022) 10;15:11786329221135424. DOI: 10.1177/11786329221135424
  35. Naidu, Livashin, Lindokuhle A. Sibiya, Okikioluwa S. Aladeyelu, and Carmen O. Rennie. “A computed tomography assessment of olfactory fossa depth in relation to Functional endoscopic sinus surgery in a South African population.” Translational Research in Anatomy 28 : 100219 2022 https://doi.org/10.1016/j.tria.2022.100219
  36. Aladeyelu, Okikioluwa Stephen, Kehinde Samuel Olaniyi, Samuel Oluwaseun Olojede, Wonder-Boy Eumane Mbatha, Andile Lindokuhle Sibiya, and Carmen Olivia Rennie. “Temporal bone pneumatization: A scoping review on the growth and size of mastoid air cell system with age.” PloS one: 17(6) : e0269360 (2022) doi: 10.1371/journal.pone.0269360
  37. Sinenhlanhla Scintilla Ziqubu and Lindokuhle Andile Sibiya. A Confounding Case of Clefts – More Than Meets the Eye. Otolaryngology Case Reports: 22: 100386, (2022). https://doi.org/10.1016/j.xocr.2021.100386
  38. S Mapipa, AL Sibiya, L Buccimazza. Blindness and ophthalmoplegia from metastatic breast carcinoma. South African Journal of Surgery, volume 6: 1 (2023) https://doi.org/10.36303/SAJS.3905
  39. Okikioluwa Stephen Aladeyelu, Samuel Oluwaseun Olojede, Sodiq Kolawole Lawal, Matome Nadab Matshipi, Andile Lindokuhle Sibiya, Carmen Olivia Rennie, Wonder-Boy Eumane Mbatha. Three-dimensional volumetric analyses of temporal bone pneumatization from early childhood to early adulthood in a South African population. (2023) Folia Morphologica. DOI: 10.5603/FM.a2023.0016
  40. Okikioluwa Stephen Aladeyelu, Samuel Oluwaseun Olojede, Sodiq Kolawole Lawal, Wonder-Boy Eumane Mbatha, Andile Lindokuhle Sibiya, Carmen Olivia Rennie. Influence of pneumatization on morphology of temporal bone-related vasculatures and their morphometric relationship with ear regions: a computed tomography study. (2023) Scientific Reports, Volume 13, issue 1 https://www.nature.com/articles/s41598-023-29295-4

 Presentation at Congress

2009    Invasive fungal sinusitis: a retrospective study and literature review. – Dr MJ Smith

2010    Provisional results: Hearing Health resources within KZN Public Health sector – Dr WP Kuhn

2010    Complicated isolated sphenoid sinusitis (poster) – Dr WP Kuhn

2010    3rd branchial pouch sinus (poster) – Dr WP Kuhn

2011    A rare case of metastatic melanoma of the EAC. (Poster) – Dr K Moodley

2012    An unusual case of primary laryngeal amyloidosis (Poster) – Dr K Moodley

2012    A rare case of Wegeners Granulomatosis presenting as a pre maxillary mass – Dr K Moodley

2013    Head and neck Haemangioma, our experience described using 4 patients and a review of the literature for current trends in management. (Poster) – Dr K Moodley

2013    A Novel way of teaching tracheostomy care in a general surgical ward – Dr PBN Ndebele

2018    Dr Reshna Mungar, won the Registrar Prize for the best oral presentation at the 2016 International  ENT Congress in Durban

2020    Presented at the ENT Congress in 2020, hosted by Gauteng. Won first place. : Anatomic variations in the frontal sinus outflow tract of paediatric patients with complicated sinusitis – Dr T Nandkishore

Presented at the ENT Congress in 2022

  • Dr SA Mapipa               (Poster) –A Tale of Two Cysts: a rare case of dual pathologies involving bilateral 
                                                              cerebellopontine angles.
  • Dr M Moyo                   (Poster) –Consider a wide differential diagnosis of mastoiditis in Immunocompromised
                                                              patients: A rare case of Nocardia Mastoiditis.
  • Dr SP Sithole                 (Oral) –Variation in Aerosol Generation by surgical modality during oropharyngeal and
                                                               laryngeal surgery
  • Dr SS Gumede              (Oral) –Neck dissection for advanced laryngeal cancer: role and relevance in KwaZulu Natal
  • Dr S Maistry                  (Oral) – Peak expiratory flow rate monitoring in recurrent respiratory papillomatosis

 Research

  • Dr TK Naidu:                 A new diagnostic application of Flow Cytometry for Head & Neck Lymphomas
  • Dr TK Naidu:                 Audit of Head & Neck Kaposi Sarcomas
  • Dr TK Naidu:                 Co-investigator for the use of Coablation in laryngeal papillomas
  • Dr TK Naidu:                 Audit of penetrating temporal bone injuries
  • Dr TK Naidu:                 Thyroid gland involvement in laryngeal carcinomas
  • Dr K Moodley:              MMed research Proposal – the impact of HIV on epithelial salivary gland Tumours in an area
                                           of high seroprevalence.
  • Dr ZB Khuzwayo:          Otogenic intracranial complications – 10 year retrospective review in South Africa, KwaZulu-
                                             Natal
  • Dr ZB Khuzwayo:          Mastoiditis in HIV positive children
  • Dr ZB Khuzwayo:          Case series of a Critical Mastoiditis in KwaZulu-Natal
  • Dr KD Schlemmer:       Stapes augmentation, Quality of life in cochlear implantation, subglottic stenosis,
                                            complicated sinusitis
  • Dr C Graham:                Development of an assessment tool that measure change of Knowledge Attitude and
                                            Practice of mothers/caregivers towards Universal Newborn Hearing Screening Programme
                                            (UNHSP) following health education intervention
  • Dr M Khan:                    Recurrent respiratory papillomatosis: a 10 year experience of adult and paediatric cases.
  • Dr R Bipath:                  Pediatric subglottic stenosis. 5 years of experience in KwaZulu Natal
  • Dr L Lukama:               Africa’s challenged ENT Services: Highlighting challenges in Zambia